Meta-analysis of effectiveness of laminectomy decompression compared with vertebral lamina decompression combined with lumbar fusion in Degree I spondylolisthesis and spinal canal stenosis

Abstract

Objective To analyze the effectiveness of laminectomy decompression compared with vertebral lamina decompression combined with lumbar fusion in Degree I spondylolisthesis and spinal canal stenosis. Methods PubMed, Science Direct Online, Springer, CNKI, Wan Fang and VIP were retrieved to collect relevant randomized controlled trials(RCT). According to inclusion and exclusion criteria, two researchers screened literatures, extracted data and evaluated quality.RevMan5.0 software was used for Meta analysis.A total of 11 RCT were included, with a total of 1684 patients.Meta analysis showed that compared with the simple laminectomy group, the VAS score of lumbar pain in the lumbar fusion group at 1 years after operation decreased (MD and 95%CI: -1.20(-1.57- -0.83), P<0.05), and the VAS score of the 1 year postoperative leg pain in the lumbar fusion group decreased(MD and 95%CI: -0.88(-1.32- -0.44), P<0.05), the excellent rate of lumbar fusion group at 2 years after operation was higher(OR and 95%CI: 1.65(1.13-2.41), P<0.05). There was no significant difference in postoperative complications and lumbar spondylolisthesis at 1 years after operation. Conclusion In long term, compared with decompression alone, vertebral lamina decompression combined with lumbar fusion has more ideal effectiveness in the treatment. Key words: Laminectomy decompression; Vertebral lamina decompression combined with lumbar fusion; DegreeⅠspondylolisthesis; Meta analysis