Meta analysis of association between dietary factors and gastric cancer in China

Abstract

Articles that was about risk factors of gastric cancer were searched through Chinese journals full-text database and VIP Chinese science and technology journals full-text database from 1989 to June 2006. The identified literatures were analyzed using Meta-analysis in order to assess the comprehensive relation between dietary factors and gastric cancer. The results showed that a total of 21 literatures were selected. The articles were all case-control study and there were 4 papers for no matching,12 papers for 1∶1 individual matching,2 papers for 1∶2 individual matching and 3 papers for 1∶3 individual matching. The cumulative cases and controls were 4332 and 7190.①Homogeneity test: OR of salted preserved food, fried food, milk, vegetables and high salt intake were homogeneous, OR of the other factors were significant heterogeneity.② Results of Meta-analysis: The pooled OR values(95%CI) of dry and hard food, salted preserved food, smoked and coasted food, pickled or preserved food, fried food, preference to hot food, high salt intake, beans and bean products, milk, vegetables and fruits were 2.74(1.72∼4.35),2.67(2.19∼3.2),2.37(1.59∼3.53), 2.30(1.74∼3.04),1.90(1.55∼2.33),1.78(1.17∼2.70), 1.51(1.37∼1.68),0.54(0.39∼0.72),0.66(0.51∼0.85), 0.69(0.62∼0.78),and 0.55(0.38∼0.79)respectively. There were no significance on association between meat intake ,peppery food intake and gastric cancer.