Abstract
To evaluate the efficacy of high frequency oscillatory ventilation (HFOV) in management of acute respiratory distress syndrome and determine whether if there is any superiority over the conventional mechanical ventilation (CMV).
Highlights
Acute respiratory distress syndrome (ARDS) is a potentially life-threatening complication that usually occurs in critically ill patients
Meta-analysis revealed that High frequency oscillatory ventilation would have the same risk of mortality as compared to conventional mechanical ventilation. (RR = 0.93, 95% CI: 0.71 to 1.21, P = 0.60)
Using Random effect model, the outcome results revealed that High frequency oscillatory ventilation would have the same risk of mortality as compared to conventional mechanical ventilation. (RR = 0.93, 95% CI: 0.71 to 1.21, P = 0.60) Figure 3A
Summary
Acute respiratory distress syndrome (ARDS) is a potentially life-threatening complication that usually occurs in critically ill patients. ARDS is characterized by diffuse lung inflammation with reduced lung compliance and impaired gas exchange [1]. ARDS’ admission rate in intensive care unit (ICU) beds has experienced an increasing trend over the past few years. There is a parallel alarming rise in mortality for patients with ARDS. A recent observational study including demonstrated that admission and mortality rate of ARDS in 50 different countries [2]. Out of 29,144 patients, 10.4% have fulfilled ARDS criteria to be admitted in ICUs, while the mortality associated with mild, moderate, and severe ARDS was 34.9%, 40.3%, and 46.1%, respectively [2]. 23% of admitted patients received mechanical ventilation as a line of management [2]
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