Messenger RNA synthesis during amino acid starvation in Escherichia coli

Abstract

Tryptophan messenger synthesis has been shown to occur during tryptophan starvation of a stringent strain. The turnover rate is much the same and the actual amount is three times as high as that found during exponential growth of a genetically derepressed strain. Tryptophan synthetase A protein synthesis proceeds during starvation of a stringent strain and not during starvation of the isogenic relaxed strain, although tryptophan messenger is also present in the latter case. Implications of these observations are discussed. These results have been extended to total messenger of Escherichia coli.