Abstract
Introduction Mesotherapy is a technique that consists in the application of multiple intradermal injections (deep dermis) with different drugs according to the conditions to be treated. It is used in different medical specialties, its use being especially interesting in pain, a prevalent symptom in our specialty. This work has aimed to assess the effectiveness and safety of this treatment in patients with chronic painful condition of the locomotor apparatus. Material and methods We conducted a prospective study of the results obtained with the application of this technique in 59 patients, referred from the Rehabilitation Service, suffering from different conditions. The medications used for pain treatment were a combination of Piroxicam, Lidocaine 1% and Pentoxifylline. The Visual Analogue Scale (VAS), the Health Questionnaire EuroQol-5D (EQ-5D Index score) and the measurement of the painful zone diameter were used to evaluate the results. The statistical analysis was conducted with the SPSS V15.0 computer program and the method consisted in a comparison of means, using the Student's T test for matched data of each of the 3 measurement instruments used. Results and conclusions None of the patients dropped out of the treatment. Their mean age was 46 years old and 74.5% of the patients were women. Neck pain was the most frequently treated condition. We have demonstrated a statistically significant improvement (p<0.001) of the painful condition of the locomotor apparatus after mesotherapy treatment, with mean decreases of 52.28 mm (95% CI: 44.78–59.79) in the VAS, 45.86 cm (95% CI: 30.97–60.75) in the lesion diameter and average increase in the EQ-5D Index score of 0.3550 (95% CI: 0.2924–0.4177). As side effects, 26% of the patients had hematomas in the application zone that resolved spontaneously. Mesotherapy is a safe and effective method for the treatment of chronic painful condition of the locomotor apparatus.
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