Abstract
Metal mediated DNA are mismatches where a metal ion bridges the base pairs and are of interest for biosensors. Here, we study THg2+T, which is known to be stabilized by base pair metal mediated bonds, and CAg+C whose stabilization mechanism is less well understood. We use a mesoscopic model and published melting temperatures of sequences containing CC or TT mismatches in the presence of the metal ions. For THg2+T we obtain a strong base pair bond potential and moderate one for CAg+C, only one stacking potential for each configuration is stronger than usual.
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