Mesoporous Silicon with Modified Surface for Plant Viruses and Their Protein Particle Sensing.

Yuriy Vashpanov,Kae Dal Kwack,Jung Young Son

doi:10.3390/s8106225

Yuriy Vashpanov, Kae Dal Kwack + Show 1 more

Open Access

https://doi.org/10.3390/s8106225

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Abstract

Changes in electric parameters of a mesoporous silicon treated by a plasma chemical etching with fluorine and hydrogen ions, under the adsorption of NEPO (Nematodetransmitted Polyhedral) plant viruses such as TORSV (Tomato Ringspot Virus), GFLV (Grapevine Fan Leaf Virus) and protein macromolecule from TORSV particles are described. The current response to the applied voltage is measured for each virus particle to investigate the material parameters which are sensitive to the adsorbed particles. The peculiar behaviors of the response are modeled by the current-voltage relationship in a MOSFET. This model explains the behavior well and the double gate model of the MOSFET informs that the mesoporous silicon is a highly sensitive means of detecting the viruses in the size range less than 50 nm.

Highlights

Biosensors based on nanotechnologies are widely investigated for the possible applications to monitor environmental pollutants [1]
Plant viruses, in particular NEPO plant viruses such as GFLV and TORSOV have the orbicular shape with a diameter about 30 nanometers
The dependence of current I ds on bias U for all curves in Fig. 3 is very similar to source-drain characteristics of the MOSFET (Metal-oxide semiconductor field emission transistor)

Summary

Introduction

Biosensors based on nanotechnologies are widely investigated for the possible applications to monitor environmental pollutants [1]. Pores in porous silicon work as a natural membrane for small biological particles. In figure 2, an atomic force microscopic image of mesoporous silicon surface and images of protein macromolecule, plant NEPO-viruses and papilloma virus particles.

Results

Conclusion