Abstract

Biology and medicine have seen great advancements in the development of enzyme nanobiosensors capable of characterizing and quantifying biomolecules.We provide an overview of mesoporous silica (MPS)-based enzyme nanobiosensors developed for biological and medical applications, and we describe significant advances in these technologies.We review progress in constructing high-performance electrochemical enzyme biosensors. We also discuss:•MCM-41 and SBA-15-modified and MPS composite electrodes for enzyme biosensing;•incorporation of biorecognition elements into MPS material electrodes for enzyme biosensing; and,•MCM-41 and SBA-15-supported electrocatalytic MPS-based electrochemical enzyme biosensors.

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