Mesoporous silica with site-isolated amine and phosphotungstic acid groups: a solid catalyst with tunable antagonistic functions for one-pot tandem reactions.

N Raveendran Shiju,Albert H Alberts,Gadi Rothenberg,Syed Khalid,David R Brown

doi:10.1002/anie.201101449

Abstract

Coniuga et impera: A bifunctional solid catalyst is prepared by combining acid and base functions on mesoporous silica supports (see picture). The co-existence of these functions is shown by a two-step reaction sequence in one pot. Excellent product yields, which cannot be obtained by separated acid and base functions in one pot, show the validity of our concept.

Highlights

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Scientists engaged in heterogeneous catalysis often cite enzymes as their model catalysts
The difficulty lies in controlling the separation between these groups and simultaneously working at practical catalyst concentrations

Summary

Introduction

Mesoporous Silica with Site-Isolated Amine and Phosphotungstic Acid Groups: A Solid Catalyst with Tunable Antagonistic Functions for One-Pot Tandem Reactions** We combine amine base functions and heteropolyacid functions on periodic mesoporous silica, obtaining an efficient and robust bifunctional acid–base solid catalyst. By grafting 3-aminopropyl groups, giving the base catalyst SB (Figure 1, middle).

Results

Conclusion