Mesoporous carbon foam, synthesized via modified Pechini method, in a new dispersant of Salep as a novel substrate for electroanalytical determination of epinephrine in the presence of uric acid

Abstract

Mesoporous carbon foam (MCF) with particular properties was prepared via a simplistic and template-free procedure. The synthesized MCF was characterized by transmission electron microscopy, field emission scanning electron microscopy, X-ray diffraction and BET surface area techniques. Porous MCF with pores diameters of 5 to 10nm provided a perfect substrate including extensive specific surface area to modify the electrodes surface. The obtained MCF was dispersed in Salep solution to prepare a stable suspension (S-MCF). The resultant composite was casted on the surface of glassy carbon electrode (GCE) to assemble the S-MCF modified GCE (S-MCF/GCE). Cyclic voltammetry (CV) was used to study the electrochemical behavior of epinephrine (Ep) and the determination of Ep was conducted by applying differential pulls voltammetry (DPV) in the presence of uric acid (UA). In the optimized conditions, the presented sensor is able to detect the concentration range of 0.1–12μM with a limit of detection of 40nM. The presented methodology possesses a reliable reproducibility, repeatability and stability in biological samples. These results proved that the S-MCF composite has a hopeful capacity in electrochemical sensors development.