Mesoporous AlPO4: A Highly Efficient Heterogeneous Catalyst for Synthesis of 5-Substituted 1H-Tetrazoles from Nitriles and Sodium Azide via [3 + 2] Cycloaddition

Abstract

Abstract The mesoporous AlPO4 with high surface area and fine mesoporous structure was prepared by a soft template method and showed excellent catalytic performance for synthesis of 5-substituted 1H-tetrazoles from various nitriles and sodium azide with excellent yields (91%–98%). The heterogeneous AlPO4 catalyst is a good candidate to substitute metal salts or other heterogeneous catalyst and has potential value for industry application.