Mesenteric fibromatosis: report of 7 cases

Abstract

Objective To invastigate the etiology, diagnosis and treatment of mesenteric fibromatosis. Methods 7 cases of mesenteric fibromatosis was admitted into our hospital from Jan 2012 to Jan 2018. Reslut Among the 7 patients, there were 2 males and 5 females, with an average age of (40+ 16)years, 4 cases had had a history of abdominal surgery and 1 case was of familial polyp, the symptoms of organ compression were the first manifestation in 4 cases, abdominal mass as the first manifestation in 2 cases.The lesions were located on small mesentery in 5 cases, on mesenteric membrane in one, and on mesorectal membrane in one.All 7 patients underwent extensive tumor resection and the margins were negative, one of the tumors was located at the level of the duodenum, invading the superior mesenteric vein and the transverse mesocolon. Immunohistochemistry results: β-catenin(+ )、Ki-67(+ ), CD117(-), CD34(-)in 7 cases, SMA(+ )in 5 cases, Desmin (+ ) in 4 cases, ER (+ ) in 3 cases. Conclusion Most patients of mesenteric fibroma have a history of previous abdominal surgery, seconded by organ compression symptoms.β-catenin (+ ) , Ki-67 (+ ) and CD117 (-), CD34 (-) contribute to pathological diagnosis, Surgery-based comprehensive treatment can achieve therapeutic effect. Key words: Fibromatosis, aggressive; Mesentery; Surgical procedures, operative