Abstract

Mesenchymal Stromal Cells In article number 2200431, Wenjun Yan, Ling Tao, and co-workers report a novel strategy for improving the curative effect of mesenchymal stromal cell (MSC)-based therapy for myocardial infarction that is achieved by bile acid- arnesoid X receptor (FXR) axis activation. FXR overexpression in MSC facilitates the response of MSC to endogenous bile acid signals, thus enhancing the survival and paracrine angiogenesis of MSC.

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