Abstract
The variants of the course of chronic herpesvirus infection in children with the involvement of several mesenteric lymph nodes in the process and the formation of inflammatory conglomerates – mesenterite (mesadenite) are considered. Possible etiological factors of mesenteritis, morphological changes in affected lymph nodes: nonspecific hyperplasia, in some cases – necrosis and suppuration, are given. Clinical cases of mesenteritis against chronic herpesvirus infections in preschool children are described with a detailed description of clinical manifestations in the form of prolonged fever, chronic intoxication, attacks of abdominal pain accompanied by an unstable stool. Dynamics of the main laboratory markers of herpesvirus activity is given, changes in the indices of instrumental methods of investigation are tracked. Possible pathogenetic mechanisms of the formation of such manifestations of the disease, the role of the systemic inflammatory response and therapeutic approaches with the use of antiviral drugs and glucocorticosteroids are discussed.
Highlights
Рассмотрены варианты течения хронической герпетической инфекции у детей с вовлечением в процесс нескольких мезентериальных лимфатических узлов и формированием воспалительных конгломератов – мезентерита
Clinical cases of mesenteritis against chronic herpesvirus infections in preschool children are described with a detailed description of clinical manifestations in the form of prolonged fever, chronic intoxication, attacks of abdominal pain accompanied by an unstable stool
Особенностью представленных случаев сочетанной герпетической инфекции у детей является формирование затяжного процесса на фоне выраженной воспалительной активности
Summary
Рассмотрены варианты течения хронической герпетической инфекции у детей с вовлечением в процесс нескольких мезентериальных лимфатических узлов и формированием воспалительных конгломератов – мезентерита (мезаденита). The variants of the course of chronic herpesvirus infection in children with the involvement of several mesenteric lymph nodes in the process and the formation of inflammatory conglomerates – mesenterite (mesadenite) are considered. После выписки в последующие месяцы отмечалась постоянная субфебрильная температура с периодическими (один раз в месяц) ее подъемами до 39°С и более в течение 4–5 дней, схваткообразными болями в животе, жидким или кашицеобразным стулом.
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