Mentoring new talent in the cell and gene therapy manufacturing sphere

Abstract

Angela Collura completed her Post Graduation in Medical Biotechnology from Bologna University, in Italy. Angela went to work in Regulatory Affairs. After that she moved to the UK and joined the core GMP team at UCL Great Ormond Street Hospital where she was involved in the operations of the cleanrooms and the manufacture of immunotherapies such as CD19 CAR-T cells for Acute Lymphoblastic Leukemia (ALL) patients in a phase I/II clinical trial. Also, she had the opportunity to work in a trial where they manufactured an ATMP that was CD25/71 allodepleted T cells in patients undergoing hematopoietic stem cells transplant. Alongside the manufacture she was involved in the patients’ immune-monitoring program. Next, Angela moved to the ATMP manufacturing and development platform at Guy’s and St. Thomas’ hospital. Here she worked as a Production Scientist first and then Senior Production Scientist in multiple clinical trial ATMPs ranging from T-Regs to Monocytes they developed and routinely manufactured for. Currently Angela works at Achilles Therapeutic where she is part of a team where they develop GMP compliant ATMP Production procedures for Achilles’ pipeline products.