Abstract
Background: In this study, screening of mental health problems among Health Care Workers (HCWs) was performed in order to assess the prevalence and severity of depression, anxiety, and perceived stress at Iran’s largest teaching hospital during the COVID-19 pandemic.
 Methods: In this cross-sectional study, HCWs who were working professionally in specific wards for COVID-19 patients were selected by availability sampling. The patients who met the inclusion criteria and answered the submitted questions were included in the study. Next, two instruments including HADS (Hospital Anxiety and Depression Scale) and PSS-4 (Perceived Stress Scale-4) were used.
 Results: The study was conducted on 306 HCWs. The mean score and standard deviation of depression, anxiety, and perceived stress were 6.33±4.10, 8.33±4.29, and 6.88±2.90, respectively. Fifty-four percent and 36.6% of the participants showed some degree of anxiety and depression, respectively.
 Conclusion: It is necessary to use screening methods for psy- chological disorders among HCWs, along with psychosocial support and appropriate psychological interventions in this field.
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