Abstract
Benign prostatic hyperplasia (BPH) and erectile dysfunction are among the commonest diagnoses in a men's health practice. BPH is common among older men. The prostate is the size of a walnut (20 cm3) in men younger than 30 years and it gradually increases in size, leading to BPH in most men older than 60 years. BPH results from epithelial and stromal cell growth, which begins in the transitional zone of the prostate and causes urinary outflow resistance. Over time, this resistance leads to detrusor muscle dysfunction, urinary retention, and lower urinary tract symptoms (LUTS). Male sexual dysfunction includes erectile dysfunction (ED), decreased libido, anatomical abnormalities (eg, Peyronie disease), and ejaculatory dysfunction. ED, defined as the inability to achieve erections firm enough for vaginal penetration, affects millions of men in the United States.
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