MENINGOTHELIOID NODULES COEXISTING WITH PULMONARY HYDATID CYST:A RARE CASE REPORT

Abstract

Meningothelioid nodules are rare and usually benign pulmonary nodules. We present this case report because it represents the first reported case of an association between meningothelioid nodules and a pulmonary hydatid cyst. A 48-year-old Turkish female patient presented with a cough and hemoptysis lasting for a week. Chest computed tomography images revealed a well-circumscribed, unilocular cystic lesion in the left lower lobe of the lung, displaying the typical “double- wall sign” of a hydatid cyst. It was decided that the patient would undergo thoracoscopic wedge resection of the hydatid cyst in the left lower lobe. Microscopic examination revealed multiple perivenular nodules composed of epithelioid cells with round to oval nuclei, a moderate amount of eosinophilic cytoplasm, and finely granular chromatin in hematoxylin-eosin sections. Whorling of tumor cells was observed focally in most areas. Some cells exhibited pseudonuclear inclusions. The surrounding lung parenchyma contained hydatid cysts. Based on these histopathological and immunohistochemistry findings, a diagnosis of a meningothelioid nodule and a hydatid cyst was made. We encountered a rare case of coexisting meningothelioid nodules and a pulmonary hydatid cyst. Careful pathological, clinical, and radiological examination are required for the definitive diagnosis of meningothelioid nodules, and they can provide an excellent prognosis with surgery.