MENINGOCOCCIC MENINGITIS TREATED WITH SULFADIAZINE AND SULFAMERAZINE: A THREE YEAR STUDY

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Article1 September 1945MENINGOCOCCIC MENINGITIS TREATED WITH SULFADIAZINE AND SULFAMERAZINE: A THREE YEAR STUDYLEWIS K. SWEET, M.D., EDITH DUMOFF-STANLEY, M.D., HARRY F. DOWLING, M.D., F.A.C.P.LEWIS K. SWEET, M.D.Search for more papers by this author, EDITH DUMOFF-STANLEY, M.D.Search for more papers by this author, HARRY F. DOWLING, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-23-3-338 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMeningococcic meningitis has been encountered with considerable frequency in the Gallinger Municipal Hospital as well as throughout the United States during the past few years. Previous reports from this clinic1, 2and from others3, 4, 5, 6have amply demonstrated the suitability of sulfadiazine and sulfamerazine for the treatment of this type of infection. The number of patients reported in each of these studies has been relatively small, however, or the period of time covered by them has been short. It still is pertinent to question the efficacy of these drugs when used in large numbers of patients treated over...Bibliography1. FELDMANSWEETDOWLING HALKHF: Sulfadiazine therapy of purulent meningitis, including its use in twenty-four consecutive patients with meningococcic meningitis, War Med., 1942, ii, 995-1007. Google Scholar2. LEPPERSWEETDOWLING MHLKHF: The treatment of meningococcic infections with sulfadiazine and sulfamerazine (sulfamethyldiazine, monomethylsulfadiazine), Jr. Am. Med. Assoc., 1943, cxxiii, 134-138. CrossrefGoogle Scholar3. DINGLETHOMASMORTON JHLAR: Treatment of meningococcic meningitis and meningococcemia with sulfadiazine, Jr. Am. Med. Assoc., 1941, cxvi, 2666-2668. CrossrefGoogle Scholar4. DANIELSSOLOMONJAQUETTE WBSWA: Meningococcic infection in soldiers, Jr. Am. Med. Assoc., 1943, cxxiii, 1-9. Google Scholar5. OLIVERANDERSON CSDG: The treatment of meningococcic meningitis with sulfamerazine, Am. Jr. Med. Sci., 1944, ccviii, 597-602. CrossrefGoogle Scholar6. GOLDRINGMAXWELLHARTMANN DRAF: Diagnosis and management of severe infections in infants and children: a review of experiences since the introduction of sulfonamide therapy. III. Meningococcal infections, Jr. Pediat., 1945, xxvi, 1-31. Google Scholar7. BENEDICT SR: The determination of blood sugar, Jr. Biol. Chem., 1925, lxiv, 207. CrossrefGoogle Scholar8. DOWLINGLEPPER HFMH: Toxic reactions following therapy with sulfapyridine, sulfathiazole and sulfadiazine, Jr. Am. Med. Assoc., 1943, cxxi, 1190-1194. CrossrefGoogle Scholar9. DOWLINGDUMOFF-STANLEYLEPPERSWEET HFEMHLK: Relative toxicity of sulfamerazine and sulfadiazine, Jr. Am. Med. Assoc., 1944, cxxv, 103-105. CrossrefGoogle Scholar10. SWEETDUMOFF-STANLEYDOWLINGLEPPER LKEHFMH: The treatment of pneumococcic meningitis with penicillin, Jr. Am. Med. Assoc., 1945, cxxvii, 263-267. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication March 26, 1945.From the Infectious Disease Service and the George Washington Medical Division, Gallinger Municipal Hospital, and the Departments of Pediatrics and Medicine, George Washington University. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMeningokokkeninfektionenREFERENCESAcute meningococcemia 1 September 1945Volume 23, Issue 3Page: 338-348KeywordsDrugsHospital medicineInfectious diseasesMeningitisPediatrics ePublished: 1 December 2008 Issue Published: 1 September 1945 PDF downloadLoading ...