Abstract
A clinical study of one hundred and forty-four cases of meningococcic meningitis, occurring during the first four months of an epidemic which began in Indianapolis in November, 1929, and in which practically all patients were admitted to the isolation wards of the City Hospital, was reported in The Journal of the American Medical Association for Sept. 13, 1930. 1 The conspicuous clinical features then observed, apart from involvement of the central nervous system, were the extreme virulence of the organism, the marked evidence of systemic infection and the death of the patients, despite rapid improvement in the changes of the spinal fluid. The high incidence of petechial hemorrhages and the large number of positive blood cultures, 63.8 per cent, were indications of the presence of a blood stream infection, and there was an apparent parallelism between the mortality rate and the number of patients with petechiae and positive blood cultures.
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