Abstract
Minocycline (7-dimethyl amino-6-demethyl tetracycline) is a tetracycline derivative that has been advocated as the drug of choice in the treatment of meningococcal carriers. The frequency and severity of side effects reported with minocycline in initial studies were infrequent and mild. We studied a group of thirty patients given minocycline as prophylaxis for a case of meningococcal meningitis who experienced a large number of side effects often limiting normal daily activity.
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