Abstract
A 51-year-old white female patient was admitted to our Intensive Care Unit, who was originally referred from Nephrology department due to neurological impairment. She had crhonic renal failure and was being treated with immunosuppressants (tacrolimus and prednisone) because she had undergone a cadaveric kidney transplantation in the past. The previous week she had been discharged after being treated for tuberculosis but she developed new symtoms including nausea, vomiting and hepatotoxicity due to the antituberculous treatment, which had to be finally stopped. Her abdominal simptomatology improved, however, she developed neurological impairment, refractory headache and tremors. On admission her temperature was 37.5oC and Glasgow coma score 13.
Highlights
A 51-year-old white female patient was admitted to our Intensive Care Unit, who was originally referred from Nephrology department due to neurological impairment
She had crhonic renal failure and was being treated with immunosuppressants because she had undergone a cadaveric kidney transplantation in the past. The previous week she had been discharged after being treated for tuberculosis but she developed new symtoms including nausea, vomiting and hepatotoxicity due to the antituberculous treatment, which had to be stopped
New sets of CSF were analysed biochemically and the results showed lymphocytic pleocytosis, raised CSF protein and reduced CSF glucose (Table 1)
Summary
A 51-year-old white female patient was admitted to our Intensive Care Unit, who was originally referred from Nephrology department due to neurological impairment She had crhonic renal failure and was being treated with immunosuppressants (tacrolimus and prednisone) because she had undergone a cadaveric kidney transplantation in the past. The previous week she had been discharged after being treated for tuberculosis but she developed new symtoms including nausea, vomiting and hepatotoxicity due to the antituberculous treatment, which had to be stopped. Her abdominal simptomatology improved, she developed neurological impairment, refractory headache and tremors. The patient suffered from several systemic complications, including septic shock, external ventricular drainage related Serratia sp meningitis and intracranial hypertension which resulted in the death of the patient 49 days after admission
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