Abstract
Meningitis is characterized by the prevalence of severe forms and it is often accompanied by life-threatening syndromes.Purpose. To determine the most informative clinical manifestations of meningitis in children in their first years of life to optimize early diagnosis and treatment.Materials and methods. The authors carried out a retrospective analytical study involving 47 cases of children hospitalized to the Republican Clinical Hospital for Infectious Diseases in 2014–2016. Their diagnose was based on the acute onset of the disease, characteristic clinical symptoms and the results of lumbar puncture. The laboratory diagnostics included a standard set of examinations.Results. Meningitis was diagnosed in 34 patients (72.3%), meningoencephalitis – in 13 patients (27.7%). 30 cases (63.8%) of meningitis / meningoencephalitis had a bacterial nature, and 9 cases (19.1%; p<0.01) had a viral nature. The most common bacterial pathogens of meningitis was Pneumococcus (10 cases), hemophilus bacillus (8). Str. agalactiae (6) and meningococcus (6). 38 (80.9%) patients had high febrile fever, 1005 of patients had weakness, drowsiness, changes in consciousness of varying severity, 29 patients (61.7%) had vomiting, 16 patients ( 34%) – headache, “brain” cry, 7 patients (15%) – hyperesthesia, a symptom of “mother’s hands”, 4 patients (8.5%) – forced posture, 34 patients (72.3%) had meningeal signs.Conclusion. The most significant symptoms of early diagnosis of meningitis in children are high febrile fever combined with drowsiness and retardation, vomiting without diarrhea.
Highlights
Meningitis is characterized by the prevalence of severe forms and it is often accompanied by life-threatening syndromes
The authors carried out a retrospective analytical study involving 47 cases of children hospitalized to the Republican Clinical Hospital for Infectious Diseases in 2014–2016
Meningitis was diagnosed in 34 patients (72.3%), meningoencephalitis – in 13 patients (27.7%). 30 cases (63.8%) of meningitis / meningoencephalitis had a bacterial nature, and 9 cases (19.1%; p
Summary
Инфекции ЦНС сохраняют свою актуальность, несмотря на совершенствование методов диагностики и лечения. Это обусловлено целым рядом причин: сложностью клинической диагностики на догоспитальном этапе, необходимостью проведения инвазивных диагностических процедур для подтверждения диагноза, особенностями терапии, связанными с физиологической «обособленностью» ЦНС, частыми осложнениями и неблагоприятным прогнозом. Одной из наиболее часто регистрируемых форм инфекционного поражения ЦНС у детей являются менингиты, заболеваемость которыми в Российской Федерации ежегодно составляет в среднем 8,22 на 100 тыс. В том числе у детей, характеризуются преобладанием тяжелых форм и частым развитием синдромов, угрожающих жизни. Что летальность при бактериальных менингитах у детей составляет в среднем 10–20%, а неврологические осложнения регистрируют у 20–40% выживших [1]. Цель исследования: определить наиболее информативные клинические проявления менингитов у детей первых лет жизни для оптимизации ранней диагностики и лечения
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More From: Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)
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