Abstract

BackgroundTo study the association between use of wireless phones and meningioma.MethodsWe performed a case–control study on brain tumour cases of both genders aged 18–75 years and diagnosed during 2007–2009. One population-based control matched on gender and age was used to each case. Here we report on meningioma cases including all available controls. Exposures were assessed by a questionnaire. Unconditional logistic regression analysis was performed.ResultsIn total 709 meningioma cases and 1,368 control subjects answered the questionnaire. Mobile phone use in total produced odds ratio (OR) = 1.0, 95% confidence interval (CI) = 0.7-1.4 and cordless phone use gave OR = 1.1, 95% CI = 0.8-1.5. The risk increased statistically significant per 100 h of cumulative use and highest OR was found in the fourth quartile (>2,376 hours) of cumulative use for all studied phone types. There was no statistically significant increased risk for ipsilateral mobile or cordless phone use, for meningioma in the temporal lobe or per year of latency. Tumour volume was not related to latency or cumulative use in hours of wireless phones.ConclusionsNo conclusive evidence of an association between use of mobile and cordless phones and meningioma was found. An indication of increased risk was seen in the group with highest cumulative use but was not supported by statistically significant increasing risk with latency. Results for even longer latency periods of wireless phone use than in this study are desirable.

Highlights

  • To study the association between use of wireless phones and meningioma

  • No conclusive evidence of an association between use of mobile and cordless phones and meningioma was found in this study

  • The results are in agreement with previous findings of no consistent evidence of an association between use of mobile and cordless phones and meningioma

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Summary

Introduction

Meningioma is the most common benign brain tumour and accounts for about 30% of intracranial tumours [1]. It develops from the pia and arachnoid membrane that cover the central nervous system. Meningioma is an encapsulated, well-demarcated and rarely malignant tumour. It is slowly growing and gives neurological symptoms by compression of adjacent structures. This tumour type is most common among middle-aged and elderly persons. There are more women than men that develop meningioma and the incidence is about two fold higher in women than men [2,3]

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