Abstract
Objetivo: revisar a literatura atualmente disponível sobre membranas para a regeneração óssea guiada na prática odontológica clínica. Material e Métodos: uma pesquisa da literatura foi realizada no PubMed, Web of Science e Scopus. A Escala de Jadad foi usada para coleta e seleção de dados. A qualidade dos estudos foi avaliada através das Diretrizes do Centro Cochrane. Ensaios clínicos randomizados e cegos publicados em português, espanhol e inglês foram incluídos. Revisões bibliográficas de estudos sem randomização e mascaramento ou quando uma percentagem igual ou superior a 20% da amostra não prosseguiu com o seguimento do estudo foram excluídos. Nós selecionamos 27 estudos que foram categorizados de acordo com os achados. Resultados: o número de publicações encontradas limitou as conclusões sobre o sucesso da GBR na odontologia. Conclusão: a variedade de técnicas e membranas aplicadas, bem como o pequeno número de estudos encontrados, carecem de estudos bem desenhados para melhor avaliar o potencial de GBR em pacientes submetidos a estas abordagens de tratamento, bem como para determinar protocolos de tratamento precisos.
Highlights
Diseases, injuries or trauma may cause tissue loss or degeneration in the human body leading to the need for treatments that facilitate its repair, replacement or regeneration.[1]
Regarding the treatment of furcation or intraosseous defects, these findings showed that guided bone regeneration through membranes was effective for resolution of cases when compared with flap surgery alone
The small number of studies that met the inclusion criteria limited the conclusions on the success of membranes for guided bone regeneration in specific dentistry areas
Summary
Injuries or trauma may cause tissue loss or degeneration in the human body leading to the need for treatments that facilitate its repair, replacement or regeneration.[1]. Tissue engineering aims at regenerating injured tissue through the development and use of biological substitutes,[3] which act as a scaffold to regenerate, maintain, improve, or stimulate the formation of new tissues.[1] The area is of interest to most dental specialties including periodontics, orthodontics, surgery, endodontics and dental implantology[1,4,5] with the need for materials capable of effective and rapid bone formation.[6]. Several methods have been developed to increase bone volume as well as to stimulate the formation of this tissue such as distraction osteogenesis,[7] osteoinduction,[8] osteoconduction[9] and guided bone regeneration (GBR).[10] The concept of Guided Bone Regeneration (GBR) is attributed to the combination of bone substitutes and membranes commonly used to restore lost or defective bone.[11]
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