Membrane Potential Imaging in the Nervous System and Heart

Abstract

Part 1 Principles of Membrane Potential-Imaging.- Historical Overview and General Methods of Membrane Potential-Imaging.- Design and Use of Organic Voltage-Sensitive Dyes.- Part 2 Membrane Potential Signals with Single Cell Resolution.- Imaging Sub millisecond Membrane Potential Changes from Individual Regions of Single Axons, Dendrites and Spines.- Combining Membrane Potential Imaging with Other Optical Techniques.- Monitoring Spiking Activity of Many Individual Neurons in Invertebrate Ganglia.- Part 3 Monitoring Activity of Networks and Large Neuronal Populations.- Monitoring Integrated Activity of Individual Neurons Using FRET-Based Voltage-Sensitive Dyes.- Monitoring Population Membrane Potential Signals from Neocortex.- Voltage Imaging in the Study of Hippocampal Circuit Function and Plasticity.- Monitoring Population Membrane Potential Signals During Development of The Vertebrate Nervous System.- Imaging the Dynamics Of Mammalian Neocortical Population Activity In-Vivo.- Imaging the Dynamics of Neocortical Population Activity in Behaving and Freely Moving Mammals.- Part 4 Monitoring Membrane Potential in the Heart.- History of Cardiac Optical Imaging.- Imaging of Ventricular Fibrillation and Defibrillation: The Virtual Electrode Hypothesis.- Optical Mapping of Ventricular Fibrillation Dynamics.- Bio photonics Modelling of Cardiac Optical Imaging.- Towards Depth-Rresolved Optical Imaging of Cardiac Electrical Activity.- Part 5 New Approaches - Potentials and Limitations.- Two-Photon Excitation of Fluorescent Voltage-Sensitive Dyes: Monitoring Membrane Potential in the Infrared.- Random-Access Multi photon Microscopy for Fast Three-Dimensional Imaging.- High Spatial Resolution Microscopy Using Holographic Illumination.- Second Harmonic Imaging of Membrane Potential.- Genetically Encoded Protein Sensors of Membrane Potential.