Abstract
Melorheostosis, also known as Leri′s disease and flowing periosteal hyperostosis, is a rare cause of pain and stiffness in a limb. The appearance is of "candle greasing" down one side of one or several bones of the body. We describe a case referred to tertiary care center with suspicion of renal cell carcinoma with diffuse bone metastasis. After reassessment, the patient was diagnosed melorheostosis with renal AV malformation. He was reassured about the benign nature of the disease and is asymptomatic.
Highlights
Melorheostosis is a rare nongenetic developmental anomaly, first described in 1922 by Leri and Joanny
Contrast-enhanced CAT scan of abdomen (CECT) revealed large multiloculated cystic mass arising from left kidney, impinging on pelvis and causing hydronephrosis [Figure 2]
Patients present at any age and both sexes are affected
Summary
Melorheostosis is a rare nongenetic developmental anomaly, first described in 1922 by Leri and Joanny. It can present at any age, and the diagnosis is made by radiography. This skeletal disorder is due to a disturbance of both intramembranous and endochondral bone formations and belongs to a group of “mixed sclerosing bone dysplasias.”. The prognosis is uncertain; and treatment, symptomatic. Numerous soft-tissue and vascular anomalies have been reported in patients with melorheostosis
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