Abstract
Melkersson-Rosenthal Syndrome (MRS) is a disease characterized by peripheral facial paralysis, facial edema and fissured tongue. Appearance of this triad is rare, generally monosymptomatic or oligosymptomatic involvement is observed and difficulties or delays in diagnosis can occur due to scarcity of the disease. One or two of the findings and presence of cheilitis granulomatosa in biopsy are sufficient for the diagnosis. Melkersson Rosenthal Syndrome should be considered in differential diagnosis of recurrent facial paralysis. Although findings of the syndrome can regress spontaneously or with medical treatment, it can take a progressive course in some patients, requiring surgical treatment (facial nerve decompression). In this article a pediatric case with diagnosis of Melkersson Rosenthal Syndrome is presented.
Highlights
Melkersson syndrome was first described with findings of peripheral facial paralysis and orofacial edema in 1928
Melkersson Rosenthal Syndrome (MRS) is a syndrome described with classical triad of recurrent orofacial edema, recurrent peripheral facial paralysis and fissured tongue
Since MRS can manifest as various clinical pictures, the diagnosis can be challenging in some cases
Summary
Melkersson syndrome was first described with findings of peripheral facial paralysis and orofacial edema in 1928. Classical triad of the disease is characterized by peripheral facial paralysis, non-pitting orofacial edema and fissured tongue (scrotal tongue, lingua plicata). These findings are seen in 18-70% of the patients where-. In patients with none of the three findings, diagnosis can be made with mucosal biopsy and these patients are identified as oligo or monosymptomatic form [4, 6,7,8]. etiology of MRS is not well known, several factors such as Herpes simplex infections, Epstein-Barr virus, Cytomegalovirus, Campylobacter jejuni, Varicella zoster, odontogenic
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