Abstract
Investigators at University of Toronto and McMaster University, Canada, report a 22-year-old woman with multiple episodes of status epilepticus and migratory cortical stroke-like lesions.
Highlights
Investigators at University of Toronto and McMaster University, Canada, report a 22-year-old woman with multiple episodes of status epilepticus and migratory cortical stroke-like lesions
Ketogenic diet and magnesium resulted in seizure freedom and decrease in frequency of stroke-like episodes following improvement of mitochondrial dysfunction
A ketogenic diet should be considered for treatment of intractable seizures and stroke-like episodes related to mitochondrial respiratory chain complex (MRC) defects
Summary
Investigators at University of Toronto and McMaster University, Canada, report a 22-year-old woman with multiple episodes of status epilepticus and migratory cortical stroke-like lesions. Ketogenic diet and magnesium resulted in seizure freedom and decrease in frequency of stroke-like episodes following improvement of mitochondrial dysfunction. Mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS) may respond to adjunctive ketogenic diet.
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