Melanoma in patients with mycosis fungoides

Arfenya E Karamova,Lyudmila F Znamenskaya,Kseniya M Aulova,Rifat R Saytburkhanov,Anastasiya A Vorontsova,Maryanna B Zhilova

doi:10.25208/vdv1288

Abstract

The development of both malignant neoplasms mycosis fungoides and cutaneous malignant melanoma is a rare condition; nevertheless, the literature describes both cases of the development of mycosis fungoides in patients with a primary diagnosis of melanoma and the detection of cutaneous malignant melanoma in patients with T-cell lymphomas of the skin. The question of the effect of previous therapy for mycosis fungoides on the risk of cutaneous malignant melanoma remains controversial. Currently, the world community is considering a possible pathogenetic relationship between these two oncopathologies. The clinical observations of the development of cutaneous malignant melanoma in 2 patients with mycosis fungoides presented in the article emphasize the importance of a thorough clinical and dermatoscopic examination of all pigmented formations for the timely detection of malignant melanocytic neoplasms, the presence of which radically affects the further choice of treatment tactics for patients.

Highlights

Согласие пациента: пациенты добровольно подписали информированное согласие на публикацию персональной медицинской информации в обезличенной форме именно в журнале «Вестник дерматологии и венерологии»
State Research Center of Dermatovenereology and Cosmetology Korolenko str., 3, bldg 6, 107076, Moscow, Russia. The development of both malignant neoplasms — mycosis fungoides and cutaneous malignant melanoma — is a rare condition; the literature describes both cases of the development of mycosis fungoides in patients with a primary diagnosis of melanoma and the detection of cutaneous malignant melanoma in patients with T-cell lymphomas of the skin
The clinical observations of the development of cutaneous malignant melanoma in 2 patients with mycosis fungoides presented in the article emphasize the importance of a thorough clinical and dermatoscopic examination of all pigmented formations for the timely detection of malignant melanocytic neoplasms, the presence of which radically affects the further choice of treatment tactics for patients

Summary

Introduction

Согласие пациента: пациенты добровольно подписали информированное согласие на публикацию персональной медицинской информации в обезличенной форме именно в журнале «Вестник дерматологии и венерологии». The clinical observations of the development of cutaneous malignant melanoma in 2 patients with mycosis fungoides presented in the article emphasize the importance of a thorough clinical and dermatoscopic examination of all pigmented formations for the timely detection of malignant melanocytic neoplasms, the presence of which radically affects the further choice of treatment tactics for patients.

Results

Conclusion