Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities.

Zeynep Eroglu,Daniel Abate‐Daga,Joseph Markowitz,Yana G Najjar,Florian A Karreth,Reena Thomas,Vernon K Sondak,Sheri L Holmen,Sunandana Chandra,Qing Chen,Inna Smalley,Michael B Atkins,Meenhard Herlyn,Nikhil I Khushalani,Kim Margolin,Jeffrey A Sosman,Isabella C Glitza,Michael A Davies,Yian Ann Chen,Marcus W Bosenberg ,Ravi K Amaravadi ,Hussein Tawbi ,James K Liu ,Kamran Ahmed ,Harriet M Kluger ,Peter Forsyth ,Keiran S.m Smalley

doi:10.1111/pcmr.12771

Melanoma central nervous system metastases: An update to approaches, challenges, and opportunities.

Zeynep Eroglu, Daniel Abate‐Daga + Show 25 more

Open Access

https://doi.org/10.1111/pcmr.12771

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Journal: Pigment cell & melanoma research	Publication Date: Feb 19, 2019
Citations: 32

Affiliation: Moffitt Cancer Center, Yale University, University of Pittsburgh Medical Center, University of Pennsylvania, Stanford University, Palo Alto University, The University of Texas MD Anderson Cancer Center, University of Utah, Northwestern University, The Wistar Institute, Georgetown University, City of Hope

#Melanoma Brain Metastasis Development #Melanoma Research Foundation + Show 8 more

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Abstract

In February 2018, the Melanoma Research Foundation and the Moffitt Cancer Center hosted the Second Summit on Melanoma Central Nervous System (CNS) Metastases in Tampa, Florida. In this white paper, we outline the current status of basic science, translational, and clinical research into melanoma brain metastasis development and therapeutic management. We further outline the important challenges that remain for the field and the critical barriers that need to be overcome for continued progress to be made in this clinically difficult area.

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