Abstract
Abstract Melamine and its analogues (cyanuric acid, ammeline and ammelide) have been identified as the cause of attributed to two serious food adulteration incidents: contaminated pet‐food in the United States in 2007 resulting in the death of perhaps a thousand cats and dogs, and adulterated infant formula in China in 2008 affecting almost 300,000 infants and children and causing at least 6 deaths (WHO, 2008). In both cases, melamine was deliberately added to products artificially inflate their protein content. Melamine toxicity is dependent on concentration. Data suggests that exposure to both melamine and cyanuric acid is more toxic than exposure to either compound individually. The U.S. Food and Drug Administration (FDA) continues to screen products, collaborate with foreign governments and their regulatory agencies, and monitor reports of contamination from international sources to help ensure that the U.S. food supply is safe.
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