Abstract

In the process of recirculation lymphocytes migrate from the blood into the surrounding tissues by adhering to and crossing the wall of high endothelial venules (1–4). Recently we and others have provided evidence that in man, like in rodents, a system of organ-specific receptors mediates lymphocyte-HEV recognition and thus presumably controls lymphocyte homing to lymphoid tissues and sites of inflammation (4–7).KeywordsHuman LymphocytePeripheral Lymph NodeHigh Endothelial VenuleSignificant Additive EffectLymphocyte RecirculationThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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