Mehanizam kontrakcije i relaksacije miometrijuma, interakcija okcitocina i prostaglandina

Vujadin Mujović,Goran Relić,Slaviša Minić,Nenad Šulović

doi:10.5937/pramed2002041r

Abstract

Regulation of uterine activity during pregnancy is due to the nature of the loss of humoral sympathetic, holinergical and peptidergic inervation. So far, nothing found that would indicated that the mechanism of premature birth and its pathogenesis different from the normal mechanism of delivery, except for different maturity of the fetus. Since a large number of substances that participate in the contraction and relaxation of miometrium (estrogen, progesterone, cortisol, etc.). Today's modern research has focused on prostaglandins and oxytocin, or their interaction. Accepting oxytocin as substance initiation deliveries it is difficult for two reasons: the level of oxytocin in the blood can not lift before the delivery and release of oxytocin remains constant during pregnancy. Oxytocin probably plays a role in support delivery for decidual cells stimulates the synthesis of uterine PGF2a.

Highlights

Regulation of uterine activity during pregnancy is due to the nature of the loss
that would indicated that the mechanism of premature birth
Since a large number of substances that participate in the contraction and relaxation of miometrium

Summary

PREGLEDNI RADOVI

MEHANIZAM KONTRAKCIJE I RELAKSACIJE MIOMETRIJUMA, INTERAKCIJA OKCITOCINA I PROSTAGLANDINA. Do sada ništa nije pronađeno što bi navelo na to da je mehanizam prevremenog porođaja i njegova patogeneza različita od normalnog mehanizma porođaja, osim različite zrelosti fetusa. Oksi-tocin verovatno igra ulogu u potpori porođaja jer stimuliše decidualne ćelije uterusa na sintezu prostaglandina F2α (PGF2α). SUMMARY Regulation of uterine activity during pregnancy is due to the nature of the loss of humoral sympathetic, holinergical and peptidergickal inervatio. Today's modern research has focused on prostaglandins and Oxytocin, or their interaction. Accepting oxytocin as substance initiation deliveries it is difficult for two reasons: the level of oxytocin in the blood can not lift before the delivery and release of oxytocin remains constant during pregnancy. Oxytocin probably plays a role in support delivery for decidual cells stimulates the synthesis of uterine PGF2α

Fiziologija aktivnosti uterusa

Supstancije koje učestvuju u kontrakciji i relaksaciji miometrijuma

Uzroci početka normalnog i prevremenog porođaja

Značaj oksitocina uterusnoj aktivnosti

Interakcija oksitocina i prostaglandina u uterusnoj aktivnosti