Abstract
Megacystis Microcolon Intestinal Hypoperistalsis Syndrome (MMIHS) is a rare congenital anomaly that is considered the most severe form of functional obstruction of the gastrointestinal tract. This devastating condition is composed of non-obstructed urinary bladder, microcolon with decreased or absent intestinal peristalsis. This study was designed to describe the incidence and outcome of MMIHS.
Highlights
Methods most frequent findings at autopsy or surgery
Malrotation was reported in 95 patients, dilated proximal small bowel in 36, short bowel in 41, and segmental stenosis of small bowel in 7
According to the obtained data, the majority of the survivors were independent of parenteral nutrition, yet, bladder dysfunction persisted and clean intermittent catheterization (CIC) has been reported
Summary
Methods most frequent findings at autopsy or surgery. malrotation was reported in 95 patients, dilated proximal small bowel in 36, short bowel in 41, and segmental stenosis of small bowel in 7. While surgical options can help in nutrition and for relief of the bowel obstruction, intestinal function does not usually improve and functional obstruction frequently recurs. The aim of this review was to determine the epidemiology and outcomes of MMIHS cases reported to date.
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