MEG frequency tagging reveals a grid-like code during attentional movements

Abstract

Grid-cells firing fields tile the environment with a 6-fold periodicity during both locomotion and visual exploration. Here, we tested, in humans, whether movements of covert attention elicit grid-like coding using frequency tagging. Participants observed visual trajectories presented sequentially at fixed rate, allowing different spatial periodicities (e.g., 4-, 6-, and 8-fold) to have corresponding temporal periodicities (e.g., 1, 1.5, and 2Hz), thus resulting in distinct spectral responses. We found a higher response for the (grid-like) 6-fold periodicity and localized this effect in medial-temporal sources. In a control experiment featuring the same temporal periodicity but lacking spatial structure, the 6-fold effect did not emerge, suggesting its dependency on spatial movements of attention. We report evidence that grid-like signals in the human medial-temporal lobe can be elicited by covert attentional movements and suggest that attentional coding may provide a suitable mechanism to support the activation of cognitive maps during conceptual navigation.