Abstract
Methods 86 patients who underwent cardiac surgery were studied, 45 of whom developed PPS (study group) and 41 have not (control group). Demographic data (gender, age, region of residence, ethnic origin) and type of surgery were collected. The severity of PPS was evaluated, based on a predefined scale. Genetic analysis determining carriage of one of the three most common MEFV gene mutations (M694V, V726A, E148Q) was performed.
Highlights
Post Pericardiotomy Syndrome (PPS) is a syndrome, which manifests with pleuropericardial inflammation and occurs in about 15-20% of patients undergoing surgery, involving the pleura, pericard or both
Carriage of MEFV mutations may explain the occurrence of this syndrome, which largely overlaps with FMF, in only part of the operated population
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Summary
MEFV mutation carriage as possible predisposition factor for the development of Post Pericardiotomy Syndrome (PPS). ID Dechtman1*, I Ben-Zvi1*, S Yael[2], R Cohen[2], E Nachum[3], A Lipey[3], L Sternik[3], E Kachel[3], Y Kassif[3], A Shinfeld[3], D Spigelstein[3], J Lavee[3], E Raanani[3], A Livneh[1]. From 8th International Congress of Familial Mediterranean Fever and Systemic Autoinflammatory Diseases Dresden, Germany. From 8th International Congress of Familial Mediterranean Fever and Systemic Autoinflammatory Diseases Dresden, Germany. 30 September - 3 October 2015
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