Abstract
It has been 10 years since the first biennial Workshop on Molecular Aspects of Myeloid Stem Cell Development, but the enthusiasm among participants at the most recent workshop remained as high as the first [1]. Once again, this workshop provided an outstanding forum in which new thought-provoking research results were presented, and there was a fostering of both old and new collaborations. The workshop was held at its usual venue, the Historic Inns of Annapolis, Annapolis, MD, May 1–4, 2005. It was organized by Dr. L. Wolff (National Cancer Institute, Bethesda, MD, USA) and by Drs. S. Ackerman and G. Nucifora (University of Illinois at Chicago, Chicago, IL, USA). As in prior workshops, the main focus continued to be the transcriptional regulation of myelopoiesis and its dysregulation in leukemia. However, highlights this year included the addition of a number of exciting new animal models for human leukemias and presentations on hematopoietic stem cells. The meeting’s small size, with a total of 80 global participants, encouraged a great deal of discussion during the scientific sessions and breaks. In the following meeting summary, the authors review highlights of the workshop that should be of particular interest to both basic scientists and clinical investigators working on aspects of normal myelopoiesis, hematopoietic stem cell biology, and mechanisms of leukemogenesis.
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