Abstract

The Tri-Service Microbiome Consortium (TSMC) was founded to enhance collaboration, coordination, and communication of microbiome research among U.S. Department of Defense (DoD) organizations. The annual TSMC symposium is designed to enable information sharing between DoD scientists and leaders in the field of microbiome science, thereby keeping DoD consortium members informed of the latest advances within the microbiome community and facilitating the development of new collaborative research opportunities. The 2020 annual symposium was held virtually on 24–25 September 2020. Presentations and discussions centered on microbiome-related topics within four broad thematic areas: (1) Enabling Technologies; (2) Microbiome for Health and Performance; (3) Environmental Microbiome; and (4) Microbiome Analysis and Discovery. This report summarizes the presentations and outcomes of the 4th annual TSMC symposium.

Highlights

  • Health and performance Exploring changes in the host gut microbiota during a controlled human infection model for Campylobacter jejuni

  • The Tri-Service Microbiome Consortium (TSMC) was founded in 2016 to enhance collaboration, coordination, and communication of microbiome research among U.S Department of Defense (DoD) organizations and to facilitate resource, material and information sharing among consortium members

  • Musculoskeletal injuries, and stress fracture in particular, are common in military populations. While these findings suggest that the gut microbiome may not play a critical role in age-related bone loss, the established connection between the gut microbiome and bone health does suggest a potential role for the gut microbiome in military relevant bone health outcomes that warrants further exploration

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Summary

Introduction

Health and performance Exploring changes in the host gut microbiota during a controlled human infection model for Campylobacter jejuni These data correlate with human fecal metabolome studies that showed that ALS patients had reduced nicotinamide levels compared to non-ALS controls that shared the same household, indicating that the gut microbiome can provide key metabolites in human interventions.

Results
Conclusion

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