Abstract

The AAPS Workshop on Oral Bioperformance and 21st Century Testing was held in Chicago, Illinois, on October 13 and 14, 2012. The main objective of the workshop was to reevaluate and discuss the use of dissolution testing in a more biorelevant scenario. When dissolution testing was introduced in the early 1970s, there was a debate whether the test should be a development or a quality control tool, and it ended up as a QC tool. With the knowledge of in vivo conditions acquired in the last decades, the dissolution test could be better developed to reflect the in vivo behavior of oral solid dosage forms.

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