Medycyna zindywidualizowana i farmakogenomika w leczeniu schorzeń centralnego układu nerwowego – przyszłość farmakoterapii czy kolejne wyzwanie dla systemu opieki zdrowotnej?

Abstract

The personalized medicine and the pharmacogenomics in treatment of central nervous system diseases – future of pharmacotherapy or next challenge for a health care system? The concept of personalized medicine has become increasingly popular and even “fashionable” within recent years, although the idea of personalization had originated in medicine much earlier than it gained its current label. Providing a therapy which is tailored to needs of a particular patient has been facilitated in selected areas of medicine by successful translation of the human genome and the developments of modern diagnostics and pharmacology. The personalized medicine is an area of development of medical and social sciences. It is also taking position within the health care system and it requires the sound sources of financing. The authors analyze the current status of knowledge on personalized medicine from the health care system’s point of view and setting the special focus on diseases of the central nervous system, including epilepsy. The on-going R&D initiatives from the field of the pharmacogenomics and the personalized medicine have been also presented in this paper.