Abstract
BackgroundWith 5.7 million deaths per year, stroke is the second cause of mortality worldwide, and 70% of these deaths occur in developing countries especially in relation to inappropriate clinical pathways and resources. The aim of our study was to assess the survival rate of stroke patients within 90 days and to identify its determinants. MethodsIt was a prospective observational cohort study over a period of 90 days after stroke. Patients were recruited between February and May 2015 in two tertiary hospitals in Yaoundé. The mortality rate was obtained by the Kaplan-Meier method. Multivariate analysis was performed using a Cox proportional hazards model. ResultsSixty-six patients were enrolled of which 54 were followed up to 90 days. The overall mortality rate was 23.2% (95% CI: 12.5–87.5), more than two-thirds of the deaths occurred within the first 30 days. The mortality rates at days 14, 30, 60 day were 9.1% (95% CI: 3.0–16.7), 14.3% (95% CI: 6.3–23.8) and 21.1% (95% CI: 10.5–31.6) respectively. High systolic blood pressure and a low Glasgow coma score on admission were independent risk factors of mortality at 90 days. ConclusionsThe stroke related mortality compels appropriate collective mobilization for an early and adequate management of stroke patients.
Highlights
About 15 million people worldwide are affected by stroke each year
This mortality is lower than the 41% and 35% found by Garbusinski et al in The Gambia in 2001 and Ekeh et al in Nigeria in 2006 respectively [8,9]
It is important to reinforce the quality of the care of stroke patients in our context, especially in the early phase of the disease
Summary
About 15 million people worldwide are affected by stroke each year. Over the last four decades, its incidence has increased by 100% in low/middle-income countries. In 2008, for the first time, its incidence was higher than that in developed countries [1]. With 5.7 million deaths a year, it is the second leading cause of death in the world after ischemic heart disease [2]. In sub-Saharan Africa, hospital-based studies have found stroke to be the leading cause of admission in neurology, with a mortality during admission going up to 43% in some cases [3,4]. In Cameroon, despite a cost of treatment averaging 1382USD (22 times the minimal monthly wage) per patient [5], intra-hospital stroke mortality remains high. The stroke medium-term survival and its determinants have sparsely studied in sub Saharan countries. The aim of our study was to assess the survival rate of stroke patients within 90 days, and to investigate the determinants of stroke-related mortality
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