Abstract
With the introduction of cyclosporin a new era in transplantation began. Improved immunosuppression was partly responsible for the exponential growth of heart transplant programs from 1984 to 1987[1]. The first successful lung transplant was performed by the Toronto Lung Transplant Croup in 1983 and, though less dramatic. there has been a steady increase in the number of lung transplant programs since that time[2]. More importantly. the increased frequency of organ transplantation has been accompanied by improved long-term survival. At the five heart and lung transplant programs represented by the authors of this chapter we found combined 1- and 5-year survival rates for heart (n=654) transplantation to be 89% and 75%. and for lung (n=196) transplantation to be 67% and 38%, respectively.
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