Abstract
Repellents are important allies in trying to prevent diseases transmitted by mosquito bites. Plants have been a source of various repellents and insecticides because they have a large reservoir of bioactive substances, in addition, their products have already been tested and are gaining space in research as a low-cost and easy-access alternative. A systematic review was carried out in the databases, Science Direct, Scielo, SciFinder, Springer, PubMed / Medline, Scopus and Web of Science, evaluated by three reviewers. Titles, abstracts and articles were analyzed in full in English, Spanish and Portuguese. To identify the articles, the following descriptors from the Medical Subject Headings (MeSH) were used: “insect repellents”, “essential oils”, “plants extract”, “repellent activity”, mosquitoes and plants. The bibliographic search resulted in 2274 records. Of these, 27 abstracts were considered potentially relevant, and at the end of the selection, 17 articles were included in their entirety. It was found that medicinal plants showed repellent activity against various species of mosquitoes, however due to the little standardization of the methodologies used and the products obtained it is necessary to develop standardized methods to guarantee the quality and reproducibility of clinical trials with medicinal plants.
Highlights
Mosquitoes are considered a serious public health problem due to serving as vectors for many important pathological conditions as well as inflicting significant discomfort through bites (Rueda, 2008; Ali et al, 2012)
The most prevalent mosquitoes that act as vectors of human diseases are Aedes (Chikungunya, Zika, Dengue, and Yellow fever), Anopheles, and Culex (Japanese encephalitis, West Nile virus, and filariasis) (Ghosh et al, 2012; Naseem et al, 2016)
We present here a systematic review of clinical articles on medicinal plants with mosquito repellent activity
Summary
Mosquitoes are considered a serious public health problem due to serving as vectors for many important pathological conditions as well as inflicting significant discomfort through bites (Rueda, 2008; Ali et al, 2012). 3500 mosquito species throughout the world, the majority of which are found in tropical and subtropical regions. Only 10% have medical and veterinary relevance (Reiter, 2001). The most prevalent mosquitoes that act as vectors of human diseases are Aedes (Chikungunya, Zika, Dengue, and Yellow fever), Anopheles (malaria and filariasis), and Culex (Japanese encephalitis, West Nile virus, and filariasis) (Ghosh et al, 2012; Naseem et al, 2016). The Zika virus is creating damage in several parts of the world, including Brazil, Africa, Pacific Island, and Southeast Asia.
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