Medicinal Plant Extraction of Zingiber Officinale Rhizome using Response Surface Methodology (RSM) and Characterization of the Product

Abstract

Ginger oleoresin is a valuable product with functional health benefits. Oleoresin has components in the form of volatile and non-volatile substances that are very easy to decompose. One of the essential components and easy-to-decompose compound is gingerol, which has improved functionality and is effective in enhancing immunity in herds of bodies. Oleoresin is a ginger rhizome extraction product full of active ingredients that may be utilized as medicines. Ginger oleoresin extract has a pale yellow, oily fat, and a unique and spicy odor. Gingerol is one of the compounds in ginger oleoresin that is easily decomposed into another substance. Gingerol (C17H26O4) is an easy compound to decompose into Shogaols (C17H24O3). Both of these compounds, whether gingerol or shogaol, have health benefits in the body, such as antioxidant, antimicrobial, anti-inflammatory, anti-allergic, and anti-cancer. The aim of the research is an initial study on the preparation of oleoresin extract with ethanol solvent using the Response Surface Method (RSM) with a three-factor experimental and two responses (yield and [6]-gingerol content). A maximum oleoresin extract yield of 7.44 % and [6]-gingerol content of 11.71% was obtained from the experimental design. The extraction of zingiber rhizomes powder was processed under the best condition at a solvent ratio (S/L) of 6.577, a temperature of 58.87°C, and the extraction process lasted 182 minutes.