Medicinal Mushroom, Ganoderma Lucidum, Improves Painful Symptoms in Patients with Restless Legs Syndrome

Abstract

Restless legs syndrome (RLS) is a prevalent sensorimotor sleep disorder that worsens quality of life. All the currently available drug treatments for RLS have limitations. Extracts of the mushroom Ganoderma lucidum (GL) have shown several beneficial biological effects in neurodegenerative diseases. The objective of the present study was to evaluate the effect of a 2-month course of GL extract on the intensity of painful RLS symptoms.