Medicinal chemistry of benzimidazole, a versatile pharmacophore

Abstract

Benzimidazole is a versatile moiety and has significant role in medicine and medicinal chemistry. The Benzimidazole moiety since discovered has been used in variety of medicine discovery in allopathic medicine. Some alkaloids used as alternative and complimentary medicines also contain benzimidazole. The pharmacophoric property of the moiety makes it versatile to be used as anti- ulcer, anti-helminthic, anti-bacterial, antiviral, and anti-histaminic agent. Here in this review the significant medicinal uses of benzimidazole moiety have been outlined.