Abstract
Adenia cissampeloides (Planch. ex Hook.) Harms is used in alternative medicine primarily for the management of hypertension and several other diseases. Isolation and GC-MS analysis of five essential oils collected fractionally and over 4 h by hydrodistillation from the dried leaves were carried out. The constituents included phytol, α-linolenic acid, n-hexadecanoic acid, hexahydrofarnesyl acetone, (13S)-8,13-epoxy-labd-14-ene, kaur-16-ene, guaiol, α-gurjunene, and α-elemene. Several bioactivities of the constituents as well as their potential applications in medicine and the pharmaceutical and pesticidal industries are discussed. Essential oils from some other plants have several constituents in common with those isolated from A. cissampeloides. The bioactivities of such plants are used to suggest other possible applications of A. cissampeloides.
Highlights
The uses of plants as medication for various health conditions are found in several countries of the world, including Nigeria.[1]
Essential oils from some other plants have several constituents in common with those isolated from A. cissampeloides
Several of the constituents of the leaf essential oil of Adenia cissampeloides (Planch. ex Hook.) Harms, such as azulene, myrtenol, camphene, cubebene, α-humulene, fatty acids, alcohols, aldehydes, secondary ketones, phytol, and phenolics are typical compounds found in essential oils
Summary
The uses of plants as medication for various health conditions are found in several countries of the world, including Nigeria.[1]. The acclaimed use of the plant in Nigeria is in the management of hypertension It has been found useful in the treatment of nervous disorders, leprosy, stress, cough, gonorrhoea, as well as antimicrobial treatment for wounds and sores.[7] The roots, leaves, and stem-bark are usually employed as curative agents. A catalogue of various uses of the plant worldwide contains additional medicinal applications of the various plant parts, which are sometimes used singly or in combination with other parts of the plant. These include an infusion of the root, stem or leaves in treating various ailments, including headache and back pain. Other possible applications of A. cissampeloides are suggested based on comparison of the constituents of the essential oils of the plant with those from other plants
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