Abstract
More than one million Americans have had ostomy surgery, and there are more than 130,000 new ostomy surgeries every year. Therefore, pharmacists need to understand how an ostomy can affect medications and how medications may affect the ostomate. This article reviews the application of basic pharmacokinetic and pharmacodynamic principles of medication use as it relates to the ostomy patient. Among the topics discussed include the use of controlled-release medications, antibiotic-associated diarrhea, discoloration of the stool and urine, and electrolye imbalance.
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