Abstract

Introduction: Medication related osteonecrosis of the jaw (MRONJ) adversely affects quality of life, producing significant morbidity. MRONJ is reported in patients taking oral and intravenous bisphosphonates as potent inhibitors of bone resorption. Concomitant use with newer medications such as RANKL inhibitors and anti-angiogenic medications also predispose to the development of jaw osteonecrosis.

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